In the field of biochemistry, cellular and molecular biology, and even in medicine, centrifugation is one of the most significant and widely applied research techniques. In technical terms, it is a process which involves the use of the centrifugal force for the sedimentation of heterogeneous mixtures with a centrifuge. In layman terms, it is nothing but a process to separate components of a complex mixture or to separate two immiscible liquids by using a centrifuge. This process is an integral part of industry and laboratory settings.
If we talk about the field of proteomics, centrifugation plays a vital role in the fundamental and necessary process of isolating proteins. It is a known fact that centrifugation is probably the most commonly used and preferred method for separating out all the non-protein material.
This process has other uses such as:-
- It is used to remove cells or other suspended particles from their surrounding milieu on either a batch or a continuous-flow basis. It also, separates a cell type different from another one.
- The process isolates viruses and macromolecules, including DNA, RNA, proteins, and lipids or establishes physical parameters of these particles from their usual observed behavior.
- Centrifugation separates the various sub-cellular organelles including nuclei, mitochondria, chloroplasts, Golgi bodies, lysosomes, peroxisomes, glyoxysomes, plasma membranes, endoplasmic reticulum, polysomic, and ribosomal subunits from the dispersed tissue.
How the separation of components achieved in centrifugation process?
The separation of the components during centrifugation is achieved by spinning a vessel containing material at a high speed. The imposed centrifugal force pushes heavier materials to the outside of the vessel (in some cases to settle down).
Centrifuge Tubes: In the whole process, the most recurring term is the centrifuge tubes. It is a laboratory device that is used for the separation of fluids, gas or liquid, based on density. It works on the principle that when the required samples are spun at a high speed, the resulting force causes the particles to separate based on their density. For example, those particles having a high density will settle down and those with less density will float.
This highly useful apparatus is found in most of the laboratories starting from academic to clinical to research laboratories. The device is extremely useful for purification of cells, sub-cellular organelles, viruses, proteins and nucleic acids.
Also, these tubes are available in different types depending upon the rotor design or the intent if use. From the large floor variety to the micro-centrifuge, there are many varieties available for the researcher.
Abdos’ range of Centrifuge Ware
Abdos is a well-known global brand in manufacturing plastic lab-ware products. We started our plastic laboratory division and its operations, back in the year 2009 envisaging a clear vision of delivering quality products that will transform the research world into a better and hassle-free one.
Our broad range of Centrifuge Ware is employed in a variety of centrifugation methods and assay investigations in laboratories. We takes pride in molding these fine lab-products from unadulterated and virgin resins that yield low extractability and leaching while using them.
The products that comprise the Centrifuge Ware are listed below
1) Micro Centrifuge Tubes, PP
2) Micro Pestles, PP
3) Centrifuge Tube Conical Bottom, PP/HDPE
4) Self Standing Centrifuge Tube
5) Centrifuge Tube Conical Bottom in Polystyrene
6) Racked Centrifuge Tube Conical Bottom
7) Rack for Micro Centrifuge Tubes, RPP
8) Rack for Micro Centrifuge Tubes, PC
9) Centrifuge Tube Box, PP
10) Swirl-01 Micro Centrifuge
These products act as consumable items in the laboratories while displaying their distinctive characteristics and fine quality during laboratory research processes.